Activated Sites
| CHLA | UCSF |
| Cincinnati | Children's National |
| MSKCC | Seattle |
| Indiana Riley | Utah |
| Phoenix Children's | Johns Hopkins |
| C.S. Mott Michigan | Chicago Lurie |
| St. Jude | CHOP |
| Miami | Colorado |
| Atlanta |
Reliance Packet Status
|
Site |
Assigned TACL Coordinator/Site activated |
Site Coordinator(s) | Type of submission | CHLA IRB Reliance Packet Status | Date of Submisison to CHLA IRB (Target or actual) | Pending Issues During Review and Start up |
| Children's Mercy | Suganya | Brittaney Spartz | NA | Approved | NA | Pending completion of study start up docs |
| Wisconsin | Liz (In Training) Suganya | Resubmission | Approved but requires resubmission | April 2026 | Pending site IRB acknowledgment, study start up and regulatory documents | |
| OHSU | Suganya | New Submission | In progress | Contingency Resolution in Progress -(Resubmitted on 3/2/2026) | ||
| Minnesota | Suganya | New Submission | In progress | |||
| Ohio-Nationwide | Suganya | New Submission | In progress |
Contingency Resolution in Progress -(Resubmitted on 3/2/2026) |
||
| UTSW | Ellynore | New Submission | In progress | March 2026 |
Requesting partial HIPAA waiver 2 IRBs require reliance at the institution |
|
| DFCI | Suganya | New Submission | In progress |
March 2026 (4th extension)
|
Original (12/29/25) |
|
| Cook | TBD | New Submission | TBD | TBD | ||
| Carolinas | Ellynore | New Submission | In progress | March 2026 | ||
| CHOC | Suganya | New Submission | Deferred until further notice | Site non-responsive | ||
| CNMC | Suganya | Resubmission of assent | In progress | Contingency Resolution in Progress - March 2026 | ||
| Atlanta | Liz (In Training) Suganya |
Melissa Schink Risa Bernard |
Resubmission of Assent/Consent | Not started | Target - April 2026 | |
| Miami | Spanish Consent Translation Submission | Not started | Target - April 2026 |
Following pre-review approval by TACL Ops, please submit to your local IRB and confirm acceptance. This local IRB approval is required prior to submission to the CHLA IRB. Resubmission of the consent will not be prioritized over other site submissions.
If your site is not listed and your site plans to participate it will be 1-2 months before your site will be submitted.
Do not send your documents to TACL Ops unless you are one of the siites in progress listed above.
All sites that have expressed an interest in this trial have been prioritized. If you site has a potential patient, this will impact prioritization and please contact tacl@chla.usc.edu and Dr. Elliot Stieglitz (Study Chair)